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Injection Lipolysis

Injection Lipolysis Summary

A nonsurgical fat reducing treatment which destroys fat cells and reduces the thickness of your adipose tissue at the site of the injection.

Length of Procedure
One hour
Starts from $500 per treatment. Treatment program costs start under $2,000 per zone
SpaMedica Clinic, Yorkville, Toronto, ON
Local Anesthesia mixed with the injection formula
Alternative Names
Mesotherapy, Lipodissolve, Lipolysis

Are You a Candidate?

Good candidates are individuals who desire a noticeable reduction in localized fat, but do not want to undergo an invasive or minimally-invasive surgery such as liposuction.

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Procedure Details

Injection lipolysis is the injection of chemical substances, which destroy fat cells and reducethe thickness of your adipose tissue. Injection lipolysis, performed safely and effectively, can result in a noticeable, localized fat reduction.

Figure 1. The abdomen of a patient undergoing Injection Lipolysis. Each injection point is marked out 2 cm apart and small amounts of the lipolytic chemical (DCPC) mixed with a local anesthetic is injected directly into the fat.

How is Injection Lipolysis fat reduction performed?

For  patients that seek injection lipolysis, your SpaMedica nurse may also recommend deploying direct injection lipolysis. Direct injection lipolysis is a technique pioneered by Dr. Mulholland whereby a lipolytic agent is injected directly into your fat. The lipolytic agent is often a specially-compounded chemical, Deoxycholate with or without Phosphatidyl Choline (DCPC), which helps to liquefy your fat cells prior to your first treatment with high-frequency focused ultrasound and the BodyFx.

The injection lipolysis treatment is performed with a very small hypodermic needle, approximately the same size as that deployed during Botox Injectable injections. The treatment DCPC chemical is mixed with diluted local anesthesia, virtually eliminating pain and discomfort.

This technique will be followed by the application of bulk heating radio frequency technology. Dr. Mulholland has been at the forefront of the development of these radio frequency fat contouring systems and the radio frequency deployed is called the BodyFx and combines skin tightening capability with permanent fat reduction.

Figure 2. The sterile injection of compounded substances like DCPD directly into the adipose tissue. The substances will destroy adipose tissue and fat cells, resulting in fat reduction and contour improvement.

What kind of anesthetic is used?

Injection lipolysis is acceptably tolerable, with modest pain, as it is performed by mixing the DCPC or lipolytic agent with local anesthesia. The chemical destruction mechanism does result in a degree of discomfort that is often treated with simple oral, non-steroidal anti-inflammatory medications. Most aesthetic treatment, such as Botox Injectable, soft tissue fillers and laser treatments have some pain associated with the procedure but achieve excellent results. The localize permanent fat reduction from injection lipolysis can be very predictable and a good option for small localized collections of fat.

How long does the procedure take?

The treatment requires approximately one hour. Most patients require a series of one to three treatments, with each treatment separated by approximately six weeks, depending upon the thickness of fat to be treated. In general, patients notice the results of their focal fat reduction after a single injection lipolysis treatment.

After Care Instructions

How long is the recovery following my injection lipolysis fat reduction treatment?

There is no down time following treatment for unwanted fat and patients can return to normal activities immediately. Occasionally, there is some redness and swelling and some patients will experience very modest bruising and discomfort in the area of the injection lipolysis treatment.


Is there any maintenance required following my Injection Lipolysis treatment?

The injection lipolysis focal fat reduction is permanent in nature and, as such, no maintenance is required to keep the dead fat cells away. However, subsequent synchronous permanent fat reduction technology treatments, such as UltraShape , Liposonix, BodyFX , Venus Freeze  and Zeltiq  can achieve more permanent fat reduction that augments the results achieved with injection lipolysis. In general, skin overlying any non-surgical liposuction area is treated as well at SpaMedica with very effective and efficient, non-invasive radio frequency skin heating devices to achieve tight skin as well as fat reduction. It is recommended that maintenance skin tightening treatments be performed once every three to four months to keep the skin tighten and firm over the permanent reduction injection lipolysis zones.

Side Effects + Risks

Contraindications include those individuals who may be pregnant and any localized areas of infection, inflammation or skin cancer over the areas to be treated.

Is the injection lipolysis treatment painful?

The Wtreatments result in a very modest degree of discomfort and most patients find this degree of discomfort entirely acceptable. Most aesthetic treatments, such as BOTOX Injectable, soft tissue fillers and even laser hair removers result in a very modest degree of discomfort and Injection Lipolysis is very similar in this regard.

Treatment Results

What kind of results can I expect following my treatment?

Injection lipolysis patients must be realistic about the modest results that can be achieved with this type of procedure. In general, after one treatment, a reduction 0.5 cm in the thickness of local fat can be achieved.

Most SpaMedica nonsurgical liposuction fat reduction patients undergo a combination series of treatments involving injection lipolysis and then high-frequency focused ultrasound, like Liposonix or UltraShape in combination with permanent fat reduction radiofrequency treatments to tighten both the skin and optimize the number of fat cells that are destroyed with the Injection Lipolysis treatment.

How long will the results from my injection lipolysis fat reduction treatment last?

The treatment results in the permanent death of the fat cells that are exposed to the chemical lipolytic agent. As such, those fat cells that have died will never return. However, just like liposuction patients, Injection lipolysis patients need to monitor their weight very carefully post treatment, to avoid any unnecessary excess carbohydrates going to either the area of treatment or to other areas which will affect their contour. If patients monitor their and control their weight, the fat reductions achieved should last permanently.

Benefits of Injection Lipolysis

  • Is effective in diminishing stubborn areas of unwanted body fat.
  • Lipolysis is an outpatient treatment with little to no downtime and minimal discomfort for the candidate.
  • No incisions required for this treatment.

Additional Procedures

Optimal results are often achieved at the SpaMedica nonsurgical liposuction fat reduction program by combining injection lipolysis with focused ultrasound treatments and other radiofrequency technologies, such as BodyFx or hypo thermal techniques, like CoolSculpting to achieve the optimal nonsurgical liposuction fat reduction outcomes. Each of these fat reduction device treatments takes approximately one hour and common treatment zones include the lower and upper abdomen, the hips and the outer and inner thighs.

How Much Will My Treatment Cost?

In general, SpaMedica’s nonsurgical liposuction programs are programmatic and multi-treatment in nature with two or more devices. Injection lipolysis  patients that undergo their SpaMedica program will receive their injection and one to two technologies such as Liposonix or UltraShape  and BodyFX in a combination of treatments that generally requires between three to six treatments. The Injection Lipolysis can be performed and paid for on its own, starting at $500 per treatment, and a second treatment can be performed 6-8 weeks after the first treatment. The total treatment cost, for a combined nonsurgical liposuction fat reduction program that includes Injection Lipolysis is generally charged per zone and the treatment price depends on the size of the zone and the number of technologies needed to optimize the permanent focal fat reduction. In general, the treatment programs costs start at less than $2,000 per zone, which is about one-third, or 30%, the price of a liposuction procedure.

Next Steps

To schedule a consultation simply call 877-712-8367 or fill out and submit the online consultation request form. A SpaMedica client service representative will promptly attend to your needs, answer any questions you may have and help you initiate your program.

Why Choose SpaMedica and Dr Mulholland?

Dr. Mulholland and SpaMedica have been at the forefront and are pioneers in injection lipolysis, nonsurgical liposuction and other non-invasive fat reduction technologies. Dr. Mulholland has spoken nationally and internationally on the permanent reduction of fat. By selecting SpaMedica and Dr. Mulholland, you will be attending a clinic with one of the world’s most experienced practitioners at the helm of the creation of the program. At SpaMedica, you receive more than one permanent reduction technology to optimize your results. Dr. Mulholland will ensure that you also get skin tightening treatment at the same time to achieve the best possible outcome.