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Restylane vs. Juvederm: What are the Key Differences?

Man undergoing a facial dermal filler procedure


Both Juvederm and Restylane are fillers with a hyaluronic acid base, plumping the skin and reducing signs of aging. However, we have many patients asking what the key differences are so they can figure out which filler is right for them – keep reading to find out!

What are Restylane Fillers?

Restylane is a filler with hyaluronic acid, known for smoothing fine lines and addressing skin concerns. It is most commonly used around the eyes, on the back of the hands, around the mouth, to enhance the lips, and to lift the cheeks. It is injected using a thin needle, and the treatment has no downtime.

What are Juvederm Fillers?

Juvederm fillers also contain hyaluronic acid and are designed to treat wrinkles. However, there are different types of injection depending on the area of the face and the severity of concern – some add volume to the lips and cheeks while others fill in fine lines around the nose and mouth. Downtime and pain associated with this treatment are little to none.

Similarities between Restylane and Juvederm

There are many similarities between Restylane and Juvederm, including the formula of the fillers (both using the same active ingredient of hyaluronic acid), their ability to address various skin and facial concerns, and the small amount of pain and downtime associated with both treatments. However, these treatments also boast a few differences.

Key Differences between Restylane and Juvederm

Restylane and Juvederm have some key differences, especially concerning the texture, results, and where each treatment can be performed.


The biggest difference between the two fillers is that Juvederm has a smooth texture while Restylane is more granular. Juvederm is often used to address the finest lines and tightest wrinkles on the face, while Restylane is used more for facial contouring and highly specific concerns. The smooth texture of Juvederm gives it a more natural look when injected into the face, while the granular nature of Restylane makes it stay in place (great for adding volume to the face or treating areas that don’t move often).


The results you receive depend on your goals, facial structure, and other factors going into the treatment. Both fillers will smooth out fine lines, restore lost volume in the face, and promote collagen production. Juvederm results are visible immediately following your treatment, while Restylane results can appear for 1-2 days. Restylane results last around 10 months, while Juvederm results last for up to a year. However, if you attend regular maintenance appointments, you can enjoy the beautiful results of both fillers for a long time.

Treatment Ares

Although both fillers are used to treat fine lines and plump areas of the face that have lost volume, Restylane is often used to treat stubborn and more severe concerns, while Juvederm is best for treating lines in difficult places, like nasolabial folds, around the eyes, and to correct the appearance of jowls. Some forms of Restylane are specifically designed to plump the lips, while Juvederm can assist with lip augmentation while addressing fine lines around the mouth.

Concerns Addressed

Juvederm and Restylane treat aging concerns such as fine lines, wrinkles, loss of volume, and hyperpigmentation. If you are experiencing a loss of volume and larger wrinkles on the face, chest, and hands, Restylane is great for addressing those concerns. If you want a refresh of your face with a focus on correcting difficult fine lines and wrinkles while lifting sagging skin in trouble areas like the neck, Juvederm is a good choice.

Which One Should You Choose?

Since there are significant differences between both types of fillers, it is best to consult with the talented SpaMedica team of doctors and nurses to determine whether Juvederm or Restylane is right for you. Both fillers boast a quick recovery time, no pain, and fabulous results – which one you choose depends entirely on your concerns, the severity of your skin issues, and your goals.

Book a Consultation Today

To achieve your best skin today, book a consultation at the SpaMedica clinic. Our highly esteemed medical team looks forward to creating your treatment plan.

By SpaMedica Infinite Vitality Clinic Non-Surgical

The team at Toronto's SpaMedica comprises a distinguished group of Canada's top dermatologists, nurses, and technicians, specializing in non-surgical cosmetic procedures. With a wealth of experience and credentials, the team expertly delivers anti-aging, body contouring, laser skin, skincare, and vaginal treatments. Known for their commitment to patient care and exceptional results, the medspa team continues to lead the industry in innovative techniques.
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