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Restylane vs. Juvederm: What are the Key Differences?

Man undergoing a facial dermal filler procedure

Both Juvéderm and Restylane are fillers with a hyaluronic acid base, plumping the skin and reducing signs of aging. However, we have many patients asking what the key differences are so they can figure out which filler is right for them – keep reading to find out!

What are Restylane Fillers?

Restylane is a filler with hyaluronic acid, known for smoothing fine lines and addressing skin concerns. It is most commonly used around the eyes, on the back of the hands, around the mouth, to enhance the lips, and to lift the cheeks. It is injected using a thin needle, and the treatment has no downtime.

What are Juvéderm Fillers?

Juvéderm fillers also contain hyaluronic acid and are designed to treat wrinkles. However, there are different types of injection depending on the area of the face and the severity of concern – some add volume to the lips and cheeks while others fill in fine lines around the nose and mouth. Downtime and pain associated with this treatment are little to none.

Comparisons of Restylane and Juvéderm

There are many similarities between Restylane and Juvéderm, including the formula of the fillers (both using the same active ingredient of hyaluronic acid), their ability to address various skin and facial concerns, and the small amount of pain and downtime associated with both treatments. However, these treatments also boast a few differences.

What is the Key Difference between Restylane and Juvéderm?

The main distinction between Restylane and Juvéderm, two common hyaluronic acid-based fillers, is their texture and consistency. Restylane’s granular consistency makes it ideal for targeting and contouring certain face areas, such as the lips and deep creases. Juvéderm, on the other hand, has a smoother consistency that allows it to spread more easily and is commonly used to treat bigger regions for a softer, more even appearance.

Principal Distinctions between Restylane and Juvéderm

Restylane and Juvéderm have some key differences, especially concerning the texture, results, and where each treatment can be performed.


The biggest difference between the two fillers is that Juvéderm has a smooth texture while Restylane is more granular. Juvéderm is often used to address the finest lines and tightest wrinkles on the face, while Restylane is used more for facial contouring and highly specific concerns. The smooth texture of Juvéderm gives it a more natural look when injected into the face, while the granular nature of Restylane makes it stay in place (great for adding volume to the face or treating areas that don’t move often).


The results you receive depend on your goals, facial structure, and other factors going into the treatment. Both fillers will smooth out fine lines, restore lost volume in the face, and promote collagen production. Juvéderm results are visible immediately following your treatment, while Restylane results can appear for 1-2 days. Restylane results last around 10 months, while Juvéderm results last for up to a year. However, if you attend regular maintenance appointments, you can enjoy the beautiful results of both fillers for a long time.

Treatment Areas

Although both fillers are used to treat fine lines and plump areas of the face that have lost volume, Restylane is often used to treat stubborn and more severe concerns, while Juvéderm is best for treating lines in difficult places, like nasolabial folds, around the eyes, and to correct the appearance of jowls. Some forms of Restylane are specifically designed to plump the lips, while Juvéderm can assist with lip augmentation while addressing fine lines around the mouth.

  • Lips: Restylane and Juvederm are effective for enhancing lip volume and defining lip shape. However, the choice between Juvederm and Restylane for lips often depends on the desired outcome. Juvederm is generally preferred for creating softer, fuller lips due to its smooth consistency that offers a plumper result, making it a popular choice for those seeking a more noticeable yet natural-appearing lip enhancement.
  • Under Eyes: Restylane is commonly used for under-eye treatments due to its firmer consistency, which helps maintain the shape in this delicate area. It effectively reduces under-eye hollows by adding volume and smoothing out the area.
  • Cheeks: Juvederm Voluma is specifically designed for cheek augmentation. Its thicker consistency provides a significant lift and volume boost lasting up to two years, making it ideal for restoring youthful contours to the cheeks.
  • Nasolabial Folds: Both fillers are suitable for softening the appearance of nasolabial folds. Restylane can be used for deeper folds because it provides more precise lift and fill, whereas Juvederm offers smoother results for less pronounced lines.


Both Juvederm and Restylane treatments typically range in cost depending on the amount of product used. The prices are comparable, though Juvederm might slightly edge higher in cost due to its longer-lasting formula.

Side Effects

Common side effects for both fillers include temporary redness, swelling, tenderness, and bruising at the injection site. These effects usually subside within a few days. Both treatments have a similar profile for mild side effects, though individual reactions can vary.

Duration (Procedure Time)

Both Juvederm and Restylane treatments are typically quick, often completed within 30 to 60 minutes per session. This makes both options convenient for patients looking for minimal downtime.

Is Juvederm Better than Restylane for Lip Filler?

Choosing between Juvederm and Restylane for lip enhancement depends on the patient’s specific aesthetic goals. Juvederm is often favoured for creating smoother, fuller lips due to its highly cohesive gel that provides a voluminous and plump appearance, which is ideal for those seeking noticeable yet natural-looking enhancement. Restylane, with its slightly firmer texture, offers precise contouring capabilities, making it excellent for defining lip shape and treating finer lines around the mouth.

Which One Should You Choose?

Since there are significant differences between both types of fillers, it is best to consult with the talented SpaMedica team of doctors and nurses to determine whether Juvéderm or Restylane is right for you. Both fillers boast a quick recovery time, no pain, and fabulous results – which one you choose depends entirely on your concerns, the severity of your skin issues, and your goals.

Book a Consultation Today

To achieve your best skin today, book a consultation at the SpaMedica clinic. Our highly esteemed medical team looks forward to creating your treatment plan.

By SpaMedica Infinite Vitality Clinic Non-Surgical

The team at Toronto's SpaMedica comprises a distinguished group of Canada's top dermatologists, nurses, and technicians, specializing in non-surgical cosmetic procedures. With a wealth of experience and credentials, the team expertly delivers anti-aging, body contouring, laser skin, skincare, and vaginal treatments. Known for their commitment to patient care and exceptional results, the medspa team continues to lead the industry in innovative techniques.
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